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Supercritical carbon dioxide extraction of four medicinal mediterranean plants : investigation of chemical composition and antioxidant activity
Čižmek, Lara (Avtor), Bavcon Kralj, Mojca (Avtor), Čož-Rakovac, Rozelindra (Avtor), Mazur, Dmitry M. (Avtor), Ul'yanovskii, Nikolai (Avtor), Likon, Marko (Avtor), Trebše, Polonca (Avtor)

URLURL - Izvorni URL, za dostop obiščite https://www.mdpi.com/1420-3049/26/18/5697 Povezava se odpre v novem oknu
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Izvleček
With everyday advances in the field of pharmaceuticals, medicinal plants have high priority regarding the introduction of novel synthetic compounds by the usage of environmentally friendly extraction technologies. Herein, a supercritical CO2 extraction method was implemented in the analysis of four plants (chamomile, St. John’s wort, yarrow, and curry plant) after which the non-targeted analysis of the chemical composition, phenolic content, and antioxidant activity was evaluated. The extraction yield was the highest for the chamomile (5%), while moderate yields were obtained for the other three plants. The chemical composition analyzed by gas chromatographyhigh-resolution mass spectrometry (GC-HRMS) and liquid chromatography-high-resolution mass spectrometry (LC-HRMS) demonstrated extraction of diverse compounds including terpenes and terpenoids, fatty acids, flavonoids and coumarins, functionalized phytosterols, and polyphenols. Voltammetry of microfilm immobilized on a glassy carbon electrode using square-wave voltammetry (SWV) was applied in the analysis of extracts. It was found that antioxidant activity obtained by SWV correlates well to 1,1-diphenyl-2-picrylhidrazine (DPPH) radical assay (R2 = 0.818) and ferric reducing antioxidant power (FRAP) assay (R2 = 0.640), but not to the total phenolic content (R 2 = 0.092). Effective results were obtained in terms of activity showing the potential usage of supercritical CO2 extraction to acquire bioactive compounds of interest.

Jezik:Angleški jezik
Ključne besede:green solvents, chamomile, yarrow, St. John's wort, curry plant, square-wave voltammetry, chromatography
Vrsta gradiva:Članek v reviji (dk_c)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:ZF - Zdravstvena fakulteta
Leto izida:2021
Št. strani:Str. 1-18
Številčenje:Vol. 26, iss. 18
UDK:543.544
ISSN pri članku:1420-3049
DOI:10.3390/ molecules26185697 Povezava se odpre v novem oknu
COBISS.SI-ID:77584387 Povezava se odpre v novem oknu
Število ogledov:61
Število prenosov:19
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
 
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Gradivo je del revije

Naslov:Molecules
Skrajšan naslov:Molecules
Založnik:MDPI
ISSN:1420-3049
COBISS.SI-ID:18462981 Povezava se odpre v novem oknu

Gradivo je financirano iz projekta

Financer:ARRS - Agencija za raziskovalno dejavnost Republike Slovenije (ARRS)
Številka projekta:J2-8162
Naslov:Zapiranje snovnih poti pri čiščenju komunalnih odpadnih voda z zelenimi tehnologijami

Financer:ARRS - Agencija za raziskovalno dejavnost Republike Slovenije (ARRS)
Številka projekta:P3-0388
Naslov:Mehanizmi varovanja zdravja

Licence

Licenca:CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:20.09.2021

Sekundarni jezik

Jezik:Ni določen
Ključne besede:zelena topila, kamilica, rman, šentjanževka, curry, voltametrija s kvadratnimi valovi, kromatografija

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