izpis_h1_title_alt

Evolution of fungal pathogens in domestic environments?
Gostinčar, Cene (Avtor), Grube, Martin (Avtor), Gunde-Cimerman, Nina (Avtor)

URLURL - Predstavitvena datoteka, za dostop obiščite http://dx.doi.org/10.1016/j.funbio.2011.03.004 Povezava se odpre v novem oknu

Izvleček
Specific indoor environments select for certain stress-tolerant fungi and can drive their evolution towards acquiring medically important traits. Here we review the current knowledge in this area of research, focussing on the so-called black yeasts. Many of these melanised stress-tolerant organisms originate in unusual ecological niches in nature, and they have a number of preadaptations that make them particularly suited for growth on human-made surfaces and substrates. Several pathogenic species have been isolated recently from various domestic habitats. We argue that in addition to enriching for - potentially - pathogenic species, the selection pressure and stress acting on microorganisms in indoor environments are driving their evolution towards acquiring the missing virulence factors and further enhancing their stress tolerance and pathogenic potential. Some of the polyextremotolerant fungi are particularly problematicČ they can grow at elevated temperatures, and so they have a higher potential to colonise warm-blooded organisms. As several species of black fungi are already implicated in health problems of various kinds, their selection and possible evolution in human environments are of concern.

Jezik:Angleški jezik
Ključne besede:black fungi, domestic environment, evolution, pathogen, polyextremophilic, polyextremotolerant
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:BF - Biotehniška fakulteta
Leto izida:2011
Št. strani:str. 1008-1018
Številčenje:Vol. 115, no. 10
UDK:579
ISSN pri članku:1878-6146
DOI:10.1016/j.funbio.2011.03.004 Povezava se odpre v novem oknu
COBISS.SI-ID:2441295 Povezava se odpre v novem oknu
Število ogledov:424
Število prenosov:161
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Gradivo je del revije

Naslov:Fungal biology
Založnik:Elsevier
ISSN:1878-6146
COBISS.SI-ID:2396239 Povezava se odpre v novem oknu

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