20.500.12556/RUL-37520 Evolution of fungal pathogens in domestic environments? Specific indoor environments select for certain stress-tolerant fungi and can drive their evolution towards acquiring medically important traits. Here we review the current knowledge in this area of research, focussing on the so-called black yeasts. Many of these melanised stress-tolerant organisms originate in unusual ecological niches in nature, and they have a number of preadaptations that make them particularly suited for growth on human-made surfaces and substrates. Several pathogenic species have been isolated recently from various domestic habitats. We argue that in addition to enriching for - potentially - pathogenic species, the selection pressure and stress acting on microorganisms in indoor environments are driving their evolution towards acquiring the missing virulence factors and further enhancing their stress tolerance and pathogenic potential. Some of the polyextremotolerant fungi are particularly problematicČ they can grow at elevated temperatures, and so they have a higher potential to colonise warm-blooded organisms. As several species of black fungi are already implicated in health problems of various kinds, their selection and possible evolution in human environments are of concern. black fungi domestic environment evolution pathogen polyextremophilic polyextremotolerant true false false Angleški jezik Angleški jezik Delo ni kategorizirano 2015-07-10 13:02:28 2015-07-10 13:02:28 2022-06-24 04:07:06 0000-00-00 00:00:00 2011 0 0 Str. 1008-1018 no. 10 Vol. 115 2011 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 579 1878-6146 10.1016/j.funbio.2011.03.004 2441295 2396239 http://dx.doi.org/10.1016/j.funbio.2011.03.004 1 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=37531 Biotehniška fakulteta 0 0 0