The effect of eggshell hydroxyapatite powder and autologous bone marrow on the healing of bone defects in rabbits

AL-Falahi, Nadia Hameed Rija (avtor), Atiyah, Ali Ghazi (avtor)

The repair of bone defects remains a challenge for clinical orthopedic surgery. Therefore, the present study was designed to evaluate the effect of using eggshell hydroxyapatite (eHA), which was prepared previously from avian eggshell by hydrothermal method and autologous bone marrow aspirated from the femoral bone, on the healing of bone gap defect on the radius bone of the right forelimb in rabbits. This study was conducted on 28 male rabbits divided randomly into four groups each (n=7); in all experimental animals (10 mm length × 2mm width), a bone gap was induced at the mid-shaft of the radius bone reaching the marrow cavity at the right forelimb. The defect in GI was left open as a control group without any additives. In GII, the bone gap was filled with eHA powder; in GIII, it was filled with eHA powder. The bone gap was filled with autologous bone marrow, and in GIV, the bone defect was equally filled with a combination of eHA and bone marrow. Experimental animals were followed up clinically, radiographically at (2, 4, 6, 8) weeks post-operatively, and histopathologically at (4, 6) weeks post-operatively. The radiological and histopathological findings revealed promising results in treated groups compared to a control group, with the best results in the combination of eHA and autologous bone marrow. In conclusion, the use of eHA and autologous bone marrow is considered a beneficial graft material in bone defect regeneration

• Jezik: Angleški jezik
• Ključne besede: hydroxyapatite, avian eggshell powder, bone gap
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: VF - Veterinarska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Datum objave: 01.01.2025
• Leto izida: 2025
• Št. strani: Str. 201-207
• Številčenje: Vol. 62, iss. 3
• PID: 20.500.12556/RUL-185482
• UDK: 636.09:611
• ISSN pri članku: 2385-8761
• DOI: 10.26873/SVR-1829-2024
• COBISS.SI-ID: 286111747
• Datum objave v RUL: 06.08.2026

Gradivo je del revije

• Naslov: Slovenian veterinary research
• Založnik: Veterinarska fakulteta, Veterinarska fakulteta, Založba Univerze v Ljubljani
• ISSN: 2385-8761
• COBISS.SI-ID: 275836160

Licence

• Licenca: CC BY-SA 4.0, Creative Commons Priznanje avtorstva-Deljenje pod enakimi pogoji 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-sa/4.0/deed.sl
• Opis: Ta licenca Creative Commons je zelo podobna običajni licenci Priznanje avtorstva, vendar zahteva, da so materialne avtorske pravice na izpeljanih delih upravljane z enako licenco.

Sekundarni jezik

• Jezik: Slovenski jezik
• Naslov: Vpliv prahu hidroksiapatita iz jajčne lupine in avtolognega kostnega mozga na celjenje kostnih poškodb pri kuncih