Estimation of rectal fluctuations during radiotherapy of rectal cancer using CBCT measured on the bone structures and the posterior rectal wall

Salmič, Klemen (avtor), Oblak, Irena (avtor), Žager Marciuš, Valerija (avtor)

This study aims to determine the deviation of the rectum from the reference position in the various parts of the rectum. Fifty neoadjuvant patients were included in the retrospective study. All patients had long-course radiotherapy. At the time of treatment, we acquired six cone-beam computed tomography (CBCT) images. The anatomical structures of the rectum and sacrum were visualized on transverse CBCT images using Eclipse software. In the upper rectum, a statistically significant difference was found between the variable's posterior ± when aligned to bone structures (p = 0.017), while when aligned to the posterior rectal wall, the variables posterior ± represent a borderline statistical significance (p = 0.051). In the lower rectum, a statistically significant difference was found between the variables left ± (p = 0.0001) and between right ± (p = 0.008) when aligned to bone structures. When aligned to the posterior rectal wall, a statistically significant difference was found between left ± (p = 0.006) and right ± (p = 0.005). Daily CBCT imaging and adaptive radiotherapy should be considered, especially in patients with tumors in the highly mobile upper third of the rectum, to minimize these deviations and ensure optimal treatment accuracy.

• Jezik: Angleški jezik
• Ključne besede: rectal carcinoma, rectal movement, preoperative radiation, alignment method
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: ZF - Zdravstvena fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Datum objave: 01.01.2025
• Leto izida: 2025
• Št. strani: Str. 57-64
• Številčenje: Vol. 40, no. 1
• PID: 20.500.12556/RUL-170941
• UDK: 616-073:616-006
• ISSN pri članku: 1451-3994
• DOI: 10.2298/NTRP2501057S
• COBISS.SI-ID: 243408131
• Datum objave v RUL: 22.07.2025

Gradivo je del revije

• Naslov: Nuclear Technology & Radiation Protection
• Skrajšan naslov: Nucl. Technol. Radiat. Prot.
• Založnik: Vinča Instituta of Nuclear Sciences
• ISSN: 1451-3994
• COBISS.SI-ID: 18296103

Licence

• Licenca: CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
• Opis: Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.

Sekundarni jezik

• Jezik: Ni določen
• Ključne besede: karcinom rektuma, rektalno gibanje, predoperativno obsevanje, metoda poravnave