20.500.12556/RUL-170941 Estimation of rectal fluctuations during radiotherapy of rectal cancer using CBCT measured on the bone structures and the posterior rectal wall This study aims to determine the deviation of the rectum from the reference position in the various parts of the rectum. Fifty neoadjuvant patients were included in the retrospective study. All patients had long-course radiotherapy. At the time of treatment, we acquired six cone-beam computed tomography (CBCT) images. The anatomical structures of the rectum and sacrum were visualized on transverse CBCT images using Eclipse software. In the upper rectum, a statistically significant difference was found between the variable's posterior ± when aligned to bone structures (p = 0.017), while when aligned to the posterior rectal wall, the variables posterior ± represent a borderline statistical significance (p = 0.051). In the lower rectum, a statistically significant difference was found between the variables left ± (p = 0.0001) and between right ± (p = 0.008) when aligned to bone structures. When aligned to the posterior rectal wall, a statistically significant difference was found between left ± (p = 0.006) and right ± (p = 0.005). Daily CBCT imaging and adaptive radiotherapy should be considered, especially in patients with tumors in the highly mobile upper third of the rectum, to minimize these deviations and ensure optimal treatment accuracy. rectal carcinoma rectal movement preoperative radiation alignment method karcinom rektuma rektalno gibanje predoperativno obsevanje metoda poravnave true false true Angleški jezik Ni določen Članek v reviji 2025-07-22 14:08:49 2025-07-22 14:08:51 2025-08-08 13:42:56 0000-00-00 00:00:00 2025 0 0 Str. 57-64 no. 1 Vol. 40 2025 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 2025-01-01 616-073:616-006 1451-3994 10.2298/NTRP2501057S 243408131 193_3-EuSPMFBookofAbstracts.pdf 193_3-EuSPMFBookofAbstracts.pdf 1 3B28842372DD85FA2985926F55466EF1 8efe820614409df18aad208f3ee831331349d440f07f0a7f630ddebb58da915e bb4e400a-67b1-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=213260 1451-39942501057S.pdf 1451-39942501057S.pdf 1 3C0AA348AFF23CB7994751CF37C10488 c1793b7064a8343874e3a4702147115104b698694444f416089bbca8f9398724 f93d73b8-66f4-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=213233 https://doiserbia.nb.rs/Article.aspx?ID=1451-39942501057S 1 ad33da54-6781-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=213234 Zdravstvena fakulteta 0 0 0