Chemotherapy is one of the most widely used treatments for cancer, but its mode of action can lead to double-edged outcomes. The portion of the medication that does not target harmful cells inevitably affects healthy tissue; reducing the propagation would therefore have a doubly positive effect. If the mixture in which the active substance is located exhibits a thixotropic response to loads, it can limit the excessive spread of the medication and consequently allow for increased control over the effect of the active substance on the tissue. This work presents the derivation of a simple, general model for predicting the time- and location-dependent distribution of the concentration of the active substance after the injection. A comparison between Newtonian and thixotropic mixtures shows the potential benefits of inducing non-constant viscous fluid properties, while a parametric analysis reveals the crucial role played by the unloaded mixture viscosity in designing a case-specific therapy.
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