Morphological and functional correlations in acute central serous chorioretinopathy

Kiraly, Peter (avtor), Šuštar Habjan, Maja (avtor), Smrekar, Jaka (avtor), Jaki Mekjavić, Polona (avtor)

Purpose We evaluate morphological and functional correlations in patients with acute central serous chorioretinopathy (CSC). Methods A prospective study was conducted on 50 patients with an acute CSC episode lasting less than 3 months. At baseline, assessments included optical coherence tomography (OCT), best-corrected visual acuity (BCVA), contrast sensitivity (CS), microperimetry (MP), and multifocal electroretinography (mfERG). A correlation analysis between OCT morphological parameters (maximal subretinal fluid height (SRF), central retinal thickness (CRT), and macular volume (MV)) and functional parameters was conducted on the affected eye for each patient. Results Among the morphological parameters, SRF showed the strongest correlations with functional parameters (r absolute value range = 0.10–0.70). Weak correlations were observed between BCVA and morphological parameters (r absolute value range = 0.14–0.26). Average retinal sensitivity (MP-A) was the functional parameter displaying the most robust negative correlation with morphological parameters (r absolute value range = 0.61–0.70). In contrast, average contrast sensitivity (CS-A) and mfERG average amplitude density in the first (mfERG-A1) and second (mfERG-A2) ring showed weak to moderate (r absolute value range = 0.35–0.56) yet statistically significantly nonzero correlations. Conclusions SRF and CRT could serve as the most representative morphological proxies for visual function deficit in acute CSC patients. Retinal sensitivity, as measured by MP, may be superior to BCVA in clinical research studies or when an in-depth visual function evaluation is needed.

• Jezik: Angleški jezik
• Ključne besede: central serous chorioretinopathy, CSC, CSR, correlations, morphological correlations, functional correlations
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta ; FMF - Fakulteta za matematiko in fiziko
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: Str. 145–153
• Številčenje: Vol. 148, iss. 3
• PID: 20.500.12556/RUL-156346
• UDK: 617.7
• ISSN pri članku: 1573-2622
• DOI: 10.1007/s10633-024-09969-8
• COBISS.SI-ID: 193402883
• Datum objave v RUL: 21.05.2024

Gradivo je del revije

• Naslov: Documenta ophthalmologica
• Skrajšan naslov: Doc. ophthalmol.
• Založnik: Springer Nature
• ISSN: 1573-2622
• COBISS.SI-ID: 513144601

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: centralna serozna horioretinopatija, korelacije, funkcionalne korelacije, morfološke korelacije