Registracija možganskih MR slik z Elastixom

Lešnjak, Ana (avtor), Simončič, Urban (mentor)

Pomembno vlogo pri medicinskem slikanju ima registracija slik. V kombinaciji s pacientovimi podatki pa je možno pridobiti dodatne klinične informacije, ki sicer na slikah niso vidne. Ravno zaradi tega je potrebno najti prostorsko razmerje med slikami. Poravnave dveh slik med sabo se lahko lotimo s programsko opremo Elastix. V diplomski nalogi sem opisala osnovni princip delovanja te opreme, predstavila pristop k registraciji in kako sem do nje pristopila, da sem dobila optimalne rezultate. Opisala in razložila sem tudi uporabljene parametre. Ker vse našteto zadeva tudi MR slike možganov, sem del naloge posvetila še razlagi, kaj MR slikanje je, ker pa sem registracijo opravljala tudi na slikah možganov Alzheimerjevih bolnikov, je nekaj zapisanega še o Alzheimerjevi bolezni. Uporabila sem togo in netogo registracijo. Slike zdravih možganov in možganov z Alzheimerjevo boleznijo sem po vizualni oceni registrirala uspešno, a vendarle menim, da bi bilo možno dobiti še boljše rezultate. Z rezultati dela sem bila zadovoljna, predvsem pa mi je bilo dragoceno učenje in izkušnja programske opreme Elastix

• Jezik: Slovenski jezik
• Ključne besede: registracija, slike, Elastix, parametri, MR, možgani, Alzheimerjeva bolezen
• Vrsta gradiva: Zaključna naloga
• Tipologija: 2.11 - Diplomsko delo
• Organizacija: FMF - Fakulteta za matematiko in fiziko
• Leto izida: 2023
• PID: 20.500.12556/RUL-150551
• COBISS.SI-ID: 165913091
• Datum objave v RUL: 20.09.2023

Sekundarni jezik

• Jezik: Angleški jezik
• Naslov: Registration of brain MR images with Elastix

Izvleček

Image registration plays an important role in medical imaging. In combination with patient data, it is possible to obtain additional clinical information that is not otherwise visible on the images. This is why it is necessary to find the spatial relationship between the images. The alignment of two images can be done using Elastix software. In my thesis I described the basic working principle of this equipment, the approach to registration and how I approached it to get optimum results. I have also described and explained the parameters used. Since all of the above also applies to brain MR images, I have devoted part of the thesis to explaining what MR imaging is, and since I have also registered brain images from Alzheimer's patients, there is some more about Alzheimer's disease. I used a rigid and non-rigid registration. I have successfully registered images of healthy brains and Alzheimer's brains by visual assessment, but I still think it would be possible to get even better results. I was pleased with the results of the work, but most of all I found the learning and experience of the Elastix software valuable.

• Ključne besede: registration, images, Elastix, parameters, MR, brain, Alzheimer’s disease