Unique relationships between phages and endospore-forming hosts

Butala, Matej (avtor), Dragoš, Anna (avtor)

As part of their survival strategy under harsh environmental conditions, endospore-forming bacteria can trigger a sporulation developmental program. Although the regulatory cascades that precisely control the transformation of vegetative bacteria into mother cells and resilient spores have been described in detail, less is known about how bacteriophages that prey on endospore-formers exploit sporulation. Herein, we argue that phages infecting these bacteria have evolved several specific molecular mechanisms, not yet known in other bacteria, that manifest from the phage-driven alliance to negative effects on the host. We anticipate that the relationships between phages and endospore-formers outlined here will inspire studies on phage ecology and evolution, and could facilitate important advances in the development of phage therapies against pathogenic spore-formers.

• Jezik: Angleški jezik
• Ključne besede: lysogeny, sporulation, Bacillus, phage–host interaction
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: BF - Biotehniška fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2023
• Št. strani: Str. 498-510
• Številčenje: Vol. 31, no. 5
• PID: 20.500.12556/RUL-145734
• UDK: 579.25/.26:578.347
• ISSN pri članku: 0966-842X
• DOI: 10.1016/j.tim.2022.11.009
• COBISS.SI-ID: 135140099
• Datum objave v RUL: 11.05.2023

Gradivo je del revije

• Naslov: Trends in microbiology
• Skrajšan naslov: Trends microbiol.
• Založnik: Elsevier
• ISSN: 0966-842X
• COBISS.SI-ID: 15452677

Licence

• Licenca: CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
• Opis: Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: ekologija mikroorganizmov, bakteriofagi, sporogene bakterije