20.500.12556/RUL-145734 Unique relationships between phages and endospore-forming hosts As part of their survival strategy under harsh environmental conditions, endospore-forming bacteria can trigger a sporulation developmental program. Although the regulatory cascades that precisely control the transformation of vegetative bacteria into mother cells and resilient spores have been described in detail, less is known about how bacteriophages that prey on endospore-formers exploit sporulation. Herein, we argue that phages infecting these bacteria have evolved several specific molecular mechanisms, not yet known in other bacteria, that manifest from the phage-driven alliance to negative effects on the host. We anticipate that the relationships between phages and endospore-formers outlined here will inspire studies on phage ecology and evolution, and could facilitate important advances in the development of phage therapies against pathogenic spore-formers. lysogeny sporulation Bacillus phage–host interaction ekologija mikroorganizmov bakteriofagi sporogene bakterije true false true Angleški jezik Slovenski jezik Članek v reviji 2023-05-11 09:58:32 2023-05-11 09:58:32 2024-02-15 03:39:41 0000-00-00 00:00:00 2023 0 0 Str. 498-510 no. 5 Vol. 31 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 579.25/.26:578.347 0966-842X 10.1016/j.tim.2022.11.009 135140099 RAZ_Butala_Matej_2023.pdf RAZ_Butala_Matej_2023.pdf 1 5957809D59CAD64DE8B630E68BC1AD31 a4b6403386926aa468307ab3e271ed180922afc3ccbcf81fcecf061ce3178e3d 56d28789-efd4-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=168731 https://www.sciencedirect.com/science/article/pii/S0966842X22003171 0 842baab8-efd4-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=168732 Biotehniška fakulteta 0 0 0