A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs

Tomsič, Katerina (avtor), Nemec Svete, Alenka (avtor)

General anesthesia increases the production of reactive oxygen species (ROS), which can exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures. Oxidative stress has been implicated in the development of cardiovascular, dermatologic, oncologic, and other diseases in dogs, as well as ischemia and reperfusion injury. Some anesthetics, such as halogenated anesthetics, have been shown to stimulate the production of ROS, while others, such as propofol, have antioxidant properties. However, the antioxidant effects of these anesthetics may not be sufficient to counteract oxidative damage at the doses used clinically. Nevertheless, the effects of anesthetics should be considered to minimize oxidative damage during anesthesia in dogs to improve the outcome of procedures requiring general anesthesia. This mini-review addresses the current knowledge on oxidative stress during inhalational and intravenous anesthesia in dogs. There is still a lack of information on the management of anesthesia in dogs with respect to oxidative stress. Further research, including comprehensive clinical studies is needed to better understand oxidative injury mechanisms and improve perioperative protocols during anesthesia in dogs.

• Jezik: Angleški jezik
• Ključne besede: anesthesia, inhalation, anesthetics, reactive oxygen species, oxidative stress, dogs, inhalational anesthetics, intravenous anesthetics
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: VF - Veterinarska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2022
• Št. strani: 10 str.
• Številčenje: Vol. 9, art. 987536
• PID: 20.500.12556/RUL-140172
• UDK: 636.7.09:616
• ISSN pri članku: 2297-1769
• DOI: 10.3389/fvets.2022.987536
• COBISS.SI-ID: 120980483
• Datum objave v RUL: 12.09.2022

Gradivo je del revije

• Naslov: Frontiers in veterinary science
• Skrajšan naslov: Front. vet. sci.
• Založnik: Frontiers Media S.A.
• ISSN: 2297-1769
• COBISS.SI-ID: 3969402

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Projekti

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P4-0053
• Naslov: Endokrini, imunski in encimski odzivi pri zdravih in bolnih živalih