20.500.12556/RUL-140172 A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs General anesthesia increases the production of reactive oxygen species (ROS), which can exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures. Oxidative stress has been implicated in the development of cardiovascular, dermatologic, oncologic, and other diseases in dogs, as well as ischemia and reperfusion injury. Some anesthetics, such as halogenated anesthetics, have been shown to stimulate the production of ROS, while others, such as propofol, have antioxidant properties. However, the antioxidant effects of these anesthetics may not be sufficient to counteract oxidative damage at the doses used clinically. Nevertheless, the effects of anesthetics should be considered to minimize oxidative damage during anesthesia in dogs to improve the outcome of procedures requiring general anesthesia. This mini-review addresses the current knowledge on oxidative stress during inhalational and intravenous anesthesia in dogs. There is still a lack of information on the management of anesthesia in dogs with respect to oxidative stress. Further research, including comprehensive clinical studies is needed to better understand oxidative injury mechanisms and improve perioperative protocols during anesthesia in dogs. anesthesia inhalation anesthetics reactive oxygen species oxidative stress dogs inhalational anesthetics intravenous anesthetics true false true Angleški jezik Ni določen Članek v reviji 2022-09-12 13:44:40 2022-09-12 13:44:40 2024-03-04 09:47:50 0000-00-00 00:00:00 2022 0 0 10 str. art. 987536 Vol. 9 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.7.09:616 2297-1769 10.3389/fvets.2022.987536 120980483 A_mini-Tomsic.pdf A_mini-Tomsic.pdf 1 C3CAC7D62F31D2B570976441CA7888C8 016af625d09a91db6ab6030f8d44f4e4df7dadd617a112a610da4ca6db44eb9a fce8c6b9-3291-11ed-92af-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=160856 https://www.frontiersin.org/articles/10.3389/fvets.2022.987536/full 1 3a46be4e-3290-11ed-92af-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=160854 Veterinarska fakulteta 0 0 0