Ozonation of amoxicillin and ciprofloxacin in model hospital wastewater to increase biotreatability

Aleksić, Severina (avtor), Žgajnar Gotvajn, Andreja (avtor), Premzl, Katarina (avtor), Kolar, Mitja (avtor), Šostar-Turk, Sonja (avtor)

Amoxicillin (AMX) and Ciprofloxacin (CIP) are antibiotics commonly used in human medicine with high environmental toxicity and poor biodegradability. They have been found in various hospital effluents and groundwater, and their environmental impact is still not fully understood. In this work, we investigated the possibility of treating model wastewaters containing the antibiotics AMX and CIP using ozonation, with the addition of H$_2$O$_2$ under various conditions, including different pH values, H$_2$O$_2$, and ozone dosages. The quantification of and treatment efficacy for antibiotic removal were determined via solid phase extraction followed by chromatographic separation by liquid chromatography coupled with tandem triple quadrupole mass spectrometry (LC/MS/MS). This analytical system is quite efficient for the detection of all major antibiotic classes, even if they are present at very low concentrations. The efficiency of ozonation was determined by measuring the TOC (Total Organic Carbon) changes after ozonation of the model wastewater and by measuring the concentration of the two antibiotics. In a sequential activated sludge process of ozone-treated model wastewater, almost complete TOC removal and an overwhelming decrease in antibiotic concentrations (up to 99%) were observed. Ozonation resulted in complete removal of AMX and CIP in less than 30 and 120 min, respectively. The results of this work indicate that ozonation could be a suitable pretreatment method to reduce the toxicity of contaminants (AMX and CIP) and improve the biodegradability of hospital wastewater.

• Jezik: Angleški jezik
• Ključne besede: antibiotics, amoxicillin (AMX), ciprofloxacin (CIP), hospital wastewater, hydrogen peroxide, ozone, water treatment, sludge, treatment
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 13 str.
• Številčenje: Vol. 10, iss. 11, art. 1407
• PID: 20.500.12556/RUL-136370
• UDK: 628.349:66.094.3-926.214:615.33
• ISSN pri članku: 2079-6382
• DOI: 10.3390/antibiotics10111407
• COBISS.SI-ID: 85418243
• Datum objave v RUL: 26.04.2022

Gradivo je del revije

• Naslov: Antibiotics
• Skrajšan naslov: Antibiotics
• Založnik: MDPI
• ISSN: 2079-6382
• COBISS.SI-ID: 522975769

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 17.11.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: antibiotiki, amoksicilin, ciprofloksacin, bolnišnične odpadne vode, ozon, vodikov peroksid, čiščenje vod