Nanotechnology meets oncology : nanomaterials in brain cancer research, diagnosis and therapy

Zottel, Alja (avtor), Videtič Paska, Alja (avtor), Jovchevska, Ivana (avtor)

Advances in technology of the past decades led to development of new nanometer scale diagnosis and treatment approaches in cancer medicine leading to establishment of nanooncology. Inorganic and organic nanomaterials have been shown to improve bioimaging techniques and targeted drug delivery systems. Their favorable physico-chemical characteristics, like small sizes, large surface area compared to volume, specific structural characteristics, and possibility to attach different molecules on their surface transform them into excellent transport vehicles able to cross cell and/or tissue barriers, including the blood-brain barrier. The latter is one of the greatest challenges in diagnosis and treatment of brain cancers. Application of nanomaterials can prolong the circulation time of the drugs and contrasting agents in the brain, posing an excellent opportunity for advancing the treatment of the most aggressive form of the brain cancer-glioblastomas. However, possible unwanted side-effects and toxicity issues must be considered before final clinical translation of nanoparticles.

• Jezik: Angleški jezik
• Ključne besede: nanomaterials, brain cancer, nanomedicine, nanoparticles, nanobodies, blood–brain barrier, glioblastoma, nanodiagnostics, nanotherapy
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2019
• Št. strani: 28 str.
• Številčenje: Vol. 12, iss. 10, art. 1588
• PID: 20.500.12556/RUL-132244
• UDK: 616-006
• ISSN pri članku: 1996-1944
• DOI: 10.3390/ma12101588
• COBISS.SI-ID: 34313945
• Datum objave v RUL: 19.10.2021

Gradivo je del revije

• Naslov: Materials
• Skrajšan naslov: Materials
• Založnik: MDPI
• ISSN: 1996-1944
• COBISS.SI-ID: 33588485

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 15.05.2019

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: nanomateriali, rak možganov, nanomedicina