Handball has an agile character, is associated with many unexpected situations, with external disturbances during movement and also with many extreme positions of body segments, which can be the cause of most injuries in handball. We discussed about most common injuries of shoulder joint in handball, namely various compression syndromes, instability and damage to the rotary cuff. Gleno-humeral joint, which is also known as the shoulder joint in the strict sense, has an extensive range of movements due to anatomical characteristics, therefore the possibility of injuries is bigger. Handball in its structure of the game contains many hand movements with an elbow above the head, which causes great mechanical strain on the shoulder joint and the muscles around it. Damage can occur due to various factors. Most often we are talking about muscle fatigue, lower muscle strength and disproportions. In the case of handball players, most often there is damage when switching from external to internal rotation and in the inhibitory stage of the target or impact. In order to ensure proper movement mechanics, we must ensure that the optimum relationship between mobility and stability is ensured. In the thesis we presented the use of the concept of preventive exercise, we presented a selection of exercises, with which we want to improve the strength, joint stabilization and flexibility. The exercises we have selected are shown in a specific sequence. With this, we wanted to ensure that the exercise is effective but still safe.