izpis_h1_title_alt

DNA encoding for an efficient 'Omics processing
Murovec, Boštjan (Avtor), Tiedje, James M. (Avtor), Stres, Blaž (Avtor)

URLURL - Predstavitvena datoteka, za dostop obiščite http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T5J-500SR9R-1&_user=4776866&_coverDate=05%2F04%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000033658&_version=1&_urlVersion=0&_userid=4776866&md5=78c89ede53f4f7ca853cb1403a642138 Povezava se odpre v novem oknu

Izvleček
The exponential growth of available DNA sequences and the increased interoperability of biological information is triggering intergoivernmental efforts aimed at increasing the access, dissemination, and analysis of sequence data. Achieving the efficient storage and processing of DNA material is an important goal that parallels well with the foreseen coding standardization on the horizon. This paper proposes novel coding approaches, for both the dissemination and processing of sequences, where the speed of the DNA processing is shown to be boosted by exploring more than the normally utilized eight bits for encoding a single nucleotide. Further gains are achived by encoding the nucleotides together with their trailing alignament information as a single 64-bit data structure. the paper also proposes a slight modification to the established FASTA scheme in order to improve on its representation of alignament information. The significance of the proposition is confirmed by the encouraging results from empirical tests.

Jezik:Angleški jezik
Ključne besede:molekularna genetika, DNK, sekvence, bioinformatika
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:BF - Biotehniška fakulteta
Leto izida:2010
Št. strani:str. 175-190
Številčenje:Vol. 100, no. 2
UDK:575
ISSN pri članku:0169-2607
DOI:10.1016/j.cmpb.2010.03.014 Povezava se odpre v novem oknu
COBISS.SI-ID:2625416 Povezava se odpre v novem oknu
Število ogledov:628
Število prenosov:112
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
 
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Naslov:Computer methods and programs in biomedicine
Skrajšan naslov:Comput. methods programs biomed.
Založnik:Elsevier
ISSN:0169-2607
COBISS.SI-ID:25260032 Povezava se odpre v novem oknu

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