This paper presents an initial experimental evaluation of non-destructive quality control of blister packs using a conventional 2D camera. Videos of 19 blister packs were acquired under three vacuum and illumination conditions, yielding 251 manually defined regions of interest per condition (of which 52 defective and 199 non-defective). Two approaches are evaluated: dense optical-flow accumulation and pixel-intensity activity analysis based on temporal band-pass filtering and energy integration. The latter achieved the best reported F1 score of 0.951 only at −250 mbarg and uniform illumination. Performance decreased at −850 mbarg and under one-sided illumination due to global deformation and illumination nonuniformity. These initial results show the limitations of indirect 2D cues and motivate depth-based sensing.
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