Using Monte Carlo computer simulations, we investigated the self-assembly of amyloid fibrils based on a two-dimensional coarse-grained model. The simulations were carried out at different densities and temperatures. We measured the system’s energy, the number of hydrogen bonds and the properties of clusters formed by the particles. Based on these measurements, we analysed particle behaviour, formed structures and the differences in behaviour between particles with different-sized side chains at various conditions.
|
