Black mulberry fruit extract attenuates valproic acid-induced toxicity by enhancing antioxidant defenses in FaO cells : research data underlying the article

Oblak, Iza (avtor), Pavlović, Nebojša (avtor), Vukmirović, Saša (avtor), Šuput, Dušan (avtor), Stilinović, Nebojša (avtor), Milisav, Irina (avtor)

This dataset contains the numerical data underlying the figures presented in the article “Mulberry fruit extract attenuates valproic acid-induced oxidative injury and increases glutathione peroxidase activity in FaO cells.” The study investigated whether black mulberry (Morus nigra L.) fruit extract modifies valproic acid-induced toxicity and oxidative stress in FaO rat hepatoma cells following acute exposure to valproic acid for 28 hours or chronic exposure for 4 weeks. The deposited data include measurements of cell viability and fitness, hepatocellular injury, oxidative status, antioxidant enzyme activities, and extracellular antioxidant capacity. The analyzed outcomes include neutral red accumulation, extracellular alanine aminotransferase activity, hydrogen peroxide production, cellular antioxidant enzyme activities, and ABTS radical-scavenging capacity, as applicable to the acute and chronic experiments. The file provides the values used to generate the article figures, including individual biological replicate values.

• Jezik: Angleški jezik
• Ključne besede: hepatotoxicity, antioxidants, plant extracts, oxidative stress, valproic acid, mulberry, liver cells
• Tipologija: 2.20 - Raziskovalni podatki
• Časovno pokritje: From 2023-02-01 to 2026-07-20
• Organizacija: MF - Medicinska fakulteta
• Leto izida: 2026
• PID: 20.500.12556/RUL-185368
• Metode zbir. podat.: Meritve in testi

Opomba

Povezan članek/Related article: Oblak, I., Pavlović, N., Vukmirović, S., Šuput, D., Stilinović, N., Milisav, I., Black mulberry fruit extract attenuates valproic acid-induced toxicity by enhancing antioxidant defenses in FaO cells, Biomolecules and Biomedicine, 2026, https://doi.org/10.17305/bb.2026.14532

• Datum objave v RUL: 03.08.2026

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Vezano na: objavo

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: hepatotoksičnost, antioksidanti, rastlinski izvlečki, oksidativni stres, valprojska kislina, murva, jetrne celice

Projekti

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P3-0019
• Naslov: Aplikativna in bazična fiziologija in patofiziologija v medicini