Trends and determinants of C virus infection among people living with HIV in Slovenia : a nationwide study, 1986–2024

Lunar, Maja M. (avtor), Seme, Katja (avtor), Poljak, Mario (avtor)

Introduction: Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) share transmission routes and cause significant morbidity and mortality worldwide. Three previous nationwide studies reported a low prevalence of HCV infection among Slovenian people living with HIV (PLWH). Methods: Data were collected de novo from 526 PLWH newly diagnosed with HIV in Slovenia between January 1st, 2014, and December 31st, 2024, and combined with data from previous studies on this topic. Results: Altogether 1,085 (93%) PLWH were tested for HCV at HIV diagnosis: 82 (7.6%) had anti-HCV antibodies (49 or 59.8% of them viremic), and three had HCV RNA only, resulting in an HCV prevalence of 7.8%. A significant increase in the prevalence of HCV infection has been observed over the last decade. HCV infection was significantly associated with female sex, foreign nationality, parenteral HIV transmission route, and non-B HIV subtype. The most frequent HCV genotypes were 1 (60%), 3 (22%), and 4 (16%), markedly different than previously found in the general population. Conclusions: The overall prevalence of HCV infection among PLWH in Slovenia remains low, but a significant increase has been observed in the last decade compared to the previous one. Such a situation requires further regular and tight monitoring to allow timely interventions if and when needed.

• Jezik: Angleški jezik
• Ključne besede: HIV, hepatitis C, prevalence, Slovenia
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2026
• Št. strani: Str. 33-36
• Številčenje: Vol. 35, iss. 1
• PID: 20.500.12556/RUL-184308
• UDK: 616.9
• ISSN pri članku: 1318-4458
• DOI: 10.15570/actaapa.2026.2
• COBISS.SI-ID: 277556739
• Datum objave v RUL: 03.07.2026

Gradivo je del revije

• Naslov: Acta dermatovenerologica Alpina, Panonica et Adriatica
• Skrajšan naslov: Acta dermatovenerolog. Alp. Panon. Adriat.
• Založnik: Association of Slovenian Dermatovenerologists
• ISSN: 1318-4458
• COBISS.SI-ID: 31649024

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: HIV, hepatitis C, prevalenca, Slovenija

Projekti

• Financer: University of Ljubljana, Faculty of Medicine, Institut of Microbiology and Immnology

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P3-0083
• Naslov: Odnosi parazitskega obstajanja