Polymicrobial purulent pericarditis and peritoneal effusion in an immunocompromised patient with Staphylococcus aureus bacteraemia : a case report

Cmor, Nino (avtor), Dora, Eva (avtor), Lainščak, Mitja (avtor), Tibaut, Miha (avtor)

Background: Polymicrobial pericarditis is an extremely rare and lethal form of pericarditis. Prompt initiation of appropriate antimicrobial treatment and pericardial drainage are crucial. Case summary: A 57-year-old immunocompromised male patient presented to the emergency department due to dyspnoea, chest pain, and fever lasting for 7 days. Following clinical, laboratory, and imaging work-up, he was found to have pericardial effusion with signs of tamponade. After pericardiocentesis through subxiphoid and apical approaches, 800 mL of gross purulent fluid was obtained. Blood and pericardial fluid cultures confirmed the diagnosis of polymicrobial purulent pericarditis (Staphylococcus aureus and Bacteroides vulgatus). Further work-up revealed minor peritoneal effusion, and paracentesis fluid culture revealed the presence of S. aureus and, additionally, Candida albicans. After treatment initiation with intravenous antibiotics, pericardial, drainage and supportive measures, the patient's condition initially improved despite the development of constrictive pericarditis. However, he suddenly deteriorated after 37 days of hospitalization and passed away after 51 days of hospitalization. Discussion: To the best of our knowledge, this is the first report of purulent pericarditis and purulent peritoneal effusion in the settings of S. aureus bacteraemia with an absent primary infection focus. Clinicians should be aware of treatment options for purulent pericarditis and consider intrapericardial fibrinolysis, especially in patients not suited for more invasive pericarditis treatment.

• Jezik: Angleški jezik
• Ključne besede: polymicrobial pericarditis, case report, pericardiocentesis, Staphylococcus aureus bacteraemia, tamponade
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.03 - Drugi znanstveni članki
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: 5 str.
• Številčenje: Vol. 8, no. 9, art. ytae427
• PID: 20.500.12556/RUL-183021
• UDK: 616.1
• ISSN pri članku: 1879-0844
• DOI: 10.1093/ehjcr/ytae427
• COBISS.SI-ID: 225957891
• Datum objave v RUL: 02.06.2026

Gradivo je del revije

• Naslov: European journal of heart failure
• Skrajšan naslov: Eur. j. heart fail.
• Založnik: Elsevier
• ISSN: 1879-0844
• COBISS.SI-ID: 23170053

Licence

• Licenca: CC BY-NC 4.0, Creative Commons Priznanje avtorstva-Nekomercialno 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc/4.0/deed.sl
• Opis: Licenca Creative Commons, ki prepoveduje komercialno uporabo, vendar uporabniki ne rabijo upravljati materialnih avtorskih pravic na izpeljanih delih z enako licenco.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: polimikrobni perikarditis, prikaz primera, perikardiocenteza, Staphylococcus aureus bakteriemija, tamponada