An overview and recent developments in the analysis of multistate processes

Gorfine, Malka (avtor), Cook, Richard John (avtor), Andersen, Per Kragh (avtor), Therneau, Terry M. (avtor), Joly, Pierre (avtor), Putter, Hein (avtor), Pohar Perme, Maja (avtor), Abrahamowicz, Michal (avtor)

Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint models for disease processes and dynamic marker processes, as well as joint models incorporating random censoring and intermittent observation times. This article reviews the ways multistate models can be formed and fitted to life history data. Recent work on pseudo-values and the incorporation of random effects to model dependence on the process history and between-process heterogeneity are also discussed. The software available to facilitate such analyses is listed.

• Jezik: Angleški jezik
• Ključne besede: frailty, process history, pseudo-values, state occupancy probability, time‐dependent covariates, transition intensity
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2026
• Št. strani: 27 str.
• Številčenje: Vol. 45, iss. 10/12, art. e70493
• PID: 20.500.12556/RUL-182758
• UDK: 311:519.24
• ISSN pri članku: 0277-6715
• DOI: 10.1002/sim.70493
• COBISS.SI-ID: 278917379
• Datum objave v RUL: 22.05.2026

Gradivo je del revije

• Naslov: Statistics in medicine
• Skrajšan naslov: Stat. med.
• Založnik: Wiley
• ISSN: 0277-6715
• COBISS.SI-ID: 502292

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: krhkost, zgodovina procesa, psevdovrednosti, verjetnost zasedenosti stanja, časovno odvisne kovariance, intenziteta prehoda