Gold nanoparticle-embedded cellulose acetate : structural, optical, mechanical, and cytotoxicity assessment

Mustapić, Mislav (avtor), Molnar, Maja (avtor), Španić, Nikola (avtor), Komar, Mario (avtor), Viljetić, Barbara (avtor), Glavaš-Obrovac, Ljubica (avtor), Heffer, Marija (avtor), Genorio, Boštjan (avtor), Ivković, Ana (avtor), Anelić, Rafael (avtor), Faraguna, Fabio (avtor), Tóth, Lázár (avtor), Budai, Judit (avtor), Márton, Zsuzsanna (avtor), Belić, Domagoj (avtor)

The development of composites with embedded gold nanoparticles (Au NPs) and biopolymeric matrices, such as cellulose acetate (CA), has gained significant attention due to their unique synergistic properties, including enhanced mechanical, physical, and thermal characteristics. In this study, a composite material consisting of Au NPs embedded in a CA matrix was prepared and thoroughly characterized and its cytotoxicity evaluated for potential medical applications such as drug delivery, biosensing, and imaging. The composite was prepared using a newly developed in situ method, ensuring mostly uniform dispersion of Au NPs within the CA matrix. Various characterization techniques, including X-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM), energy-dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS), UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), dynamic mechanical analyses (DMA), thermogravimetric analysis (TGA), and cell viability assay were employed to evaluate the structural, mechanical, thermal and biocompatibility properties of the as-prepared composite. The obtained results indicate that even a miniscule content of Au NPs (<0.14 wt%) within the CA matrix can significantly change the properties of such composites. The produced materials are compact, flexible, strong, and exhibit low cytotoxicity, making them suitable for a wide range of potential applications.

• Jezik: Angleški jezik
• Ključne besede: gold nanoparticles, cellulose acetate, composite materials, in situ synthesis, characterization techniques, biocompatibility
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2026
• Št. strani: Str. 798-812
• Številčenje: Vol. 7, iss. 2
• PID: 20.500.12556/RUL-181648
• UDK: 661.728.82:620.3
• ISSN pri članku: 2633-5409
• DOI: 10.1039/D5MA00764J
• COBISS.SI-ID: 262569987
• Datum objave v RUL: 10.04.2026

Gradivo je del revije

• Naslov: Materials advances
• Založnik: Royal Society of Chemistry
• ISSN: 2633-5409
• COBISS.SI-ID: 56274691

Licence

• Licenca: CC BY-NC 3.0, Creative Commons Priznanje avtorstva-Nekomercialno 3.0 Nedoločena
• Povezava: https://creativecommons.org/licenses/by-nc/3.0/deed.sl
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Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: zlati nanodelci, celulozni acetat, composite materials, in situ sinteza, tehnike karakterizacije, biokompatibilnost