Disentangling large-scale brain dynamics and their links to behavior during the emotional face matching task

Korponay, Cole (avtor), Cohen-Gilbert, Julia E. (avtor), Cheng, You (avtor), Kumar, Poornima (avtor), Harnett, Nathaniel G. (avtor), Medina, Adrian A. (avtor), Forester, Brent P. (avtor), Ressler, Kerry J. (avtor), Demšar, Jure (avtor), Frederick, Blaise B. (avtor), Beckmann, Christian F. (avtor), Harper, David G. (avtor), Nickerson, Lisa D. (avtor)

Emotion processing engages multiple large-scale brain networks. However, prior investigations relying on a priori, contrast-based models of brain activity obscure networks’ distinct temporal dynamics and roles in task performance. Here, we performed tensor independent component analysis to identify and track concurrent brain processes, including those with non-canonical dynamics, during the emotional face matching task (EFMT) in healthy young adults (n = 413; n = 416 replication). Ten EFMT-recruited large-scale brain networks were identified, reflecting flexible recoupling of visual association cortex to diverse non-visual networks. These networks collectively engaged 74% of cortex and more strongly explained variability in cognition and a performance-based index of emotion interference than contrast-based amygdala activation/connectivity. Variability in EFMT-recruited network activity was more strongly linked to variability in cognition than affect. Findings reveal a rich landscape of brain activity under the surface of contrast-based fMRI analyses and deepen insights into the distinct brain processes underlying subcomponents of emotional face processing.

• Jezik: Angleški jezik
• Ključne besede: neuroimaging, functional mri, brain dynamics, task analysis
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FRI - Fakulteta za računalništvo in informatiko
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2025
• Št. strani: 11 str.
• Številčenje: Vol. 8, Art. 1176
• PID: 20.500.12556/RUL-175517
• UDK: 004.9:612.82
• ISSN pri članku: 2399-3642
• DOI: 10.1038/s42003-025-08543-5
• COBISS.SI-ID: 245345027
• Datum objave v RUL: 30.10.2025

Gradivo je del revije

• Naslov: Communications biology
• Skrajšan naslov: Commun. biolog.
• Založnik: Springer Nature
• ISSN: 2399-3642
• COBISS.SI-ID: 5134671

Licence

• Licenca: CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
• Opis: Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: nevrološko slikanje, funkcijska magnetna resonanca, dinamike v možganih, analiza nalog

Projekti

• Financer: NIH - National Institutes of Health
• Program financ.: NATIONAL INSTITUTE ON AGING
• Številka projekta: 1RF1AG078304-01
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