Antioxidant strategies for age-related oxidative damage in dogs

Muršec, Aljaž (avtor), Poljšak, Borut (avtor), Nemec Svete, Alenka (avtor), Erjavec, Vladimira (avtor)

This review examines the effects of oxidative stress on the aging process in canines, focusing on the role of antioxidants in the prevention of age-related diseases. Oxidative stress is caused by an imbalance between the production of free radicals and the body’s antioxidant defenses, resulting in damage to cell structures. Dogs, especially older animals, are particularly susceptible to such damage, which contributes to the development of cognitive impairment, chronic disease and a reduced quality of life. Antioxidants such as vitamins C and E, coenzyme Q10 and polyphenols play an important role in neutralizing free radicals and mitigating oxidative damage. Various studies confirm that these antioxidants can improve overall health, slow cognitive decline and reduce the risk of diseases such as osteoarthritis, cancer and heart disease. The results suggest that an appropriate diet supplemented with antioxidants can significantly contribute to a better quality of life for dogs. However, given that some studies report limited or no effects, additional long-term clinical trials are warranted to validate the reproducibility and degree of presented benefits.

• Jezik: Angleški jezik
• Ključne besede: oxidative stress, antioxidants, aging, dogs, cognitive dysfunction
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: ZF - Zdravstvena fakulteta ; VF - Veterinarska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2025
• Št. strani: 22 str.
• Številčenje: Vol. 12, iss. 10, art. 962
• PID: 20.500.12556/RUL-175213
• UDK: 636.09:616
• ISSN pri članku: 2306-7381
• DOI: 10.3390/vetsci12100962
• COBISS.SI-ID: 252941827
• Datum objave v RUL: 20.11.2025

Gradivo je del revije

• Naslov: Veterinary sciences
• Skrajšan naslov: Vet. sci.
• Založnik: MDPI AG
• ISSN: 2306-7381
• COBISS.SI-ID: 523429657

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Projekti

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P4-0053-2019
• Naslov: Endokrini, imunski in encimski odzivi pri zdravih in bolnih živalih

• Financer: ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
• Številka projekta: P3-0388-2022
• Naslov: Mehanizmi varovanja zdravja