With advances in treatment, chronic kidney disease (CKD) has shifted from a life-threatening to a chronic condition, prompting increased attention to the psychological aspects of the disease. Patients with CKD often experience symptoms of anxiety and depression, along with reduced quality of life. The aim of this study was to examine the mental health of patients with early-stage CKD and overweight. The sample included 40 adults with stage 2 to 4 CKD and overweight or obesity. Participants completed the BDI-II, STAI, and SF-36v2® questionnaires, and data was collected on the number of diagnoses and medications, body mass index (BMI), and waist circumference. Additionally, three open-ended questions were posed to gain deeper insight into patients’ experiences of disease. The results showed somewhat lower levels of depressive and anxiety symptoms, and less impaired quality of life compared to findings reported in studies abroad. We found assotiation between higher levels of depressive and anxiety symptoms and lower quality of life, with anxiety emerging as a stronger predictor of both mental and physical components of quality of life. Older and retired individuals reported lower levels of anxiety and higher mental component of quality of life. Women reported higher levels of both depression and anxiety than men. No associations were found between indicators of burden of disease and mental health variables. The qualitative part of the study revealed which lifestyle changes patients had implemented, highlighted obstacles for lifestyle changee, and identified common worries. It also showed the importance of social support and raised questions about locus of control and the role of denial. This thesis represents the first study of its kind in Slovenia and, despite its limitations, provides valuable insight into mental health of patients with CKD before the onset of renal replacement therapy and offers a foundation for future research.
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