Introduction:Infertility and burnout represent significant public health challenges increasingly affecting individuals of reproductive age, The cumulative burden of unresolved stressors may precipitate burnout syndrome, which disrupts internal homeostasis. This dysregulation results in alterations of neuroendocrine functioning, thereby exerting adverse effects on reproductive health. After one year of unsuccessful conception, reduced fertility is clinically classified as infertility, a condition that constitutes a demanding and emotionally burdensome life period for couples. Such circumstances are frequently accompanied by negative affective states and psychological distress, further contributing to the manifestation of burnout. Purpose: The purpose of this thesis is to explore the relationship between burnout and fertility in couples of reproducitve age. Methods: A descriptive method was used, combined with a systematic review of scientific and professional literature. The search was limited to the las 5 year, with the inclusion of older studies from 2015, 2016 and 2019that were still relevant to the research topic. Only freely accessible full- text scientific and professional literature in Slovenian and English was included, provided it was content-relevant and published within the defined timeframe. Literature was searched through online search engines and databases including PubMed/Medline, ScienceDirect, CINAHL, and Google Scholar. A total of 14 studies were included in the analysis and the selection progress is presented in the PRISM diagram. The included studies were of lower methological quality.Results: The findings indicate that chronic stress or circumstances that may lead to burnout, have negative impact on the neuroendocrine system, sexual functioning and ultimately fertility. Furthermore, infertility and its treatment represent a stressful period that often causes negative emotions, strained relationships and sexual dysfunctions, all of which may lead to burnout. Discussion and conclusion: Psychological support for couples, starting at the stage of family planing, is essential, as it helps improve relationships, manage stressful situations and reduce the likelihood of discontinuing assisted reproductive treatment. Research highlights the importance of educating healthcare professionals about the symptoms of burnout and establishing multidisciplinary team to provide comprehensive support for couples. Midwifes and nurses play a key role in this process, as they are often the first point of contact for couples during familiy planing.
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