This thesis presents the design and implementation of a printed circuit board for the analog-to-digital conversion of electroporation pulses with galvanic isolation. Electroporation pulses are short, high-voltage signals that require fast, precise, and safe acquisition circuits. The main problem addressed in this work is how to reliably digitize such pulses while ensuring the protection of both the measurement system and the user through proper galvanic isolation.
To address this problem, an analysis of existing research and seminar work was carried out, followed by the preparation of a bill of materials and the selection of suitable integrated circuits. Three schematics were created in Altium Designer: for current measurement, voltage measurement, and power supply.
In the PCB design phase, the board size was set to 110 × 95 mm, and components were arranged according to functional blocks. Particular attention was paid to galvanic isolation, which required the definition of keep-out zones, insulation distances, and a board cutout to achieve the required creepage distance. The PCB was designed as a two-layer board, with the top layer mainly used for signal routing and the bottom layer serving primarily as a ground plane.
At the core of the circuit is the 16-bit ADC LTC2387-16, capable of sampling rates up to 15 Msps. Digital isolation was implemented using ADN4620/4621 isolators, while power isolation was achieved with MEJ1S0505SC DC/DC converters, ensuring separate supplies for the high-voltage and low-voltage domains.
The outcome of this work is a complete schematic and PCB layout that meets both safety and functional requirements for the acquisition of electroporation pulses. The main conclusion is that with proper component selection, careful layout, and adherence to isolation rules, a reliable measurement interface for high-voltage pulses can be realized, enabling safe and accurate signal digitization for further processing.
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