This thesis compares two synthetic approaches for the preparation of carboxyfluorescein: a classical condensation using methanesulfonic acid and a synthesis in an ionic liquid based on N-methyl-2-pyrrolidone. The first method yielded a pure product with characteristic spectral features, while the ionic liquid approach was less efficient and required further optimization. The results indicate that the classical method is currently more reliable, whereas the use of ionic liquid offers an interesting alternative for future development.
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