Deviation of the upper, middle and lower thirds of the rectum during irradiation of rectum cancer

Salmič, Klemen (avtor), Žager Marciuš, Valerija (avtor), Oblak, Irena (avtor)

Background In patients with rectal cancer, daily fluctuations in rectal volume often lead to large deformations of the target volume that cannot be corrected by adjusting the radiation couch. The main aim of the study was to determine the deviation of all three thirds of the rectum from the reference position and to determine whether these deviations are influenced by the alignments to the bony structures (the sacrum) and the posterior rectal wall. Patients and methods The conduct of the study was divided into review of the database, contouring of the anatomic structures on the cone-beam computed tomography (CBCT) images, data collection of the deviations and data output, with the alignment to the bony structures (the sacrum) - and the alignment to the posterior rectal wall performed separately. Results Fifty preoperatively irradiated patients were included in the study. The analysis revealed statistically significant differences in terms of alignment to the bony structures for different variations of the rectal thirds in the anterior (+), posterior (+), posterior (−), left (−), right (+) and right (−) directions. With regard to the alignment to the posterior rectal wall, the analysis showed statistically significant differences for different variations of the rectal thirds in directions anterior (+), posterior (+), posterior (−), left (−), right (+), right (−) and bone (+). (The positive value (+) means that the rectum was larger and the negative value (−) means that the rectum is smaller than in the reference position of the CT simulator images.) Conclusions The position of the rectal thirds changes daily in alignment with the bony structures (the sacrum), and in alignment with the posterior rectal wall.

• Jezik: Angleški jezik
• Ključne besede: rectal movement, rectal cancer, preoperative radiotherapy, radiotherapy
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: ZF - Zdravstvena fakulteta ; MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Datum objave: 01.01.2025
• Leto izida: 2025
• Št. strani: Str. 277-284
• Številčenje: Vol. 59, no. 2
• PID: 20.500.12556/RUL-169989
• UDK: 616-07
• ISSN pri članku: 1581-3207
• DOI: 10.2478/raon-2025-0020
• COBISS.SI-ID: 240925443
• Datum objave v RUL: 01.07.2025

Gradivo je del revije

• Naslov: Radiology and oncology
• Založnik: Association of Radiology and Oncology
• ISSN: 1581-3207
• COBISS.SI-ID: 784507

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.