Sustainable furfural valorization : screening amine transaminases and amine donors for efficient furfurylamine synthesis : research data underlying the article

Božinović, Marko (avtor), Šketa, Borut (avtor), Gaber, Aljaž (avtor), Jereb, Marjan (avtor), Košmrlj, Janez (avtor), Žnidaršič Plazl, Polona (avtor)

The growing global demand for furfurylamine (FA) underscores the need for environmentally friendly production methods. To address this, we explored a biocatalytic approach using transaminase (TA) for furfural (FUR) amination. Our main goal was to find an effective enzyme and cost-efficient amine donor for FA production. Screening various enzymes and amine donors revealed that FA synthesis occurred only with a tetrameric $N$-His$_6$-ATA-wt enzyme and ($S$)-(−)-α-methylbenzylamine (MBA) as the amine donor at equimolar concentrations. This method yielded 96% FA in 30 minutes, the highest reported efficiency. The proposed reaction operates at 30°C with minimal energy and material consumption, offering a promising sustainable route for FA synthesis.

• Jezik: Angleški jezik
• Ključne besede: furfural, furfurylamine, transaminase, biomass valorization, green chemistry
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Leto izida: 2024
• PID: 20.500.12556/RUL-159748
• Metode zbir. podat.: Meritve in testi
• Datum objave v RUL: 22.07.2024

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: furfural, furfurilamin, transaminaze, valorizacija biomase, zelena kemija