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The role of isoflavones in the prevention of breast cancer and prostate cancer
ID
Pejčić, Tomislav
(
Avtor
),
ID
Zeković, Milica
(
Avtor
),
ID
Bumbaširević, Uroš
(
Avtor
),
ID
Kalaba, Milica
(
Avtor
),
ID
Vovk, Irena
(
Avtor
),
ID
Bensa, Maja
(
Avtor
),
ID
Popović, Lazar
(
Avtor
),
ID
Tešić, Živoslav
(
Avtor
)
PDF - Predstavitvena datoteka,
prenos
(1,99 MB)
MD5: 3E11E730047B8D56D5F2CA762643BB88
URL - Izvorni URL, za dostop obiščite
https://www.mdpi.com/2076-3921/12/2/368
Galerija slik
Izvleček
This narrative review summarizes epidemiological studies on breast cancer and prostate cancer with an overview of their global incidence distribution to investigate the relationship between these diseases and diet. The biological properties, mechanisms of action, and available data supporting the potential role of isoflavones in the prevention of breast cancer and prostate cancer are discussed. Studies evaluating the effects of isoflavones in tissue cultures of normal and malignant breast and prostate cells, as well as the current body of research regarding the effects of isoflavones attained through multiple modifications of cellular molecular signaling pathways and control of oxidative stress, are summarized. Furthermore, this review compiles literature sources reporting on the following: (1) levels of estrogen in breast and prostate tissue; (2) levels of isoflavones in the normal and malignant tissue of these organs in European and Asian populations; (3) average concentrations of isoflavones in the secretion of these organs (milk and semen). Finally, particular emphasis is placed on studies investigating the effect of isoflavones on tissues via estrogen receptors (ER).
Jezik:
Angleški jezik
Ključne besede:
isoflavones
,
breast cancer
,
prostate cancer
Vrsta gradiva:
Članek v reviji
Tipologija:
1.02 - Pregledni znanstveni članek
Organizacija:
ZF - Zdravstvena fakulteta
Status publikacije:
Objavljeno
Različica publikacije:
Objavljena publikacija
Leto izida:
2023
Št. strani:
27 str.
Številčenje:
Vol. 12, iss. 2, art. 368
PID:
20.500.12556/RUL-155399
UDK:
616
ISSN pri članku:
2076-3921
DOI:
10.3390/antiox12020368
COBISS.SI-ID:
142086147
Datum objave v RUL:
29.03.2024
Število ogledov:
419
Število prenosov:
17
Metapodatki:
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Objavi na:
Gradivo je del revije
Naslov:
Antioxidants
Skrajšan naslov:
Antioxidants
Založnik:
MDPI
ISSN:
2076-3921
COBISS.SI-ID:
522976025
Licence
Licenca:
CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:
http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:
To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Sekundarni jezik
Jezik:
Slovenski jezik
Ključne besede:
medicina
,
bolezni
,
rakava obolenja
,
epidemiološke študije
,
rak dojke
,
rak prostate
,
hrana
Projekti
Financer:
MESTD - Ministry of Education, Science and Technological Development of Republic of Serbia
Številka projekta:
451-03-68/2022-14/200168
Financer:
MESTD - Ministry of Education, Science and Technological Development of Republic of Serbia
Številka projekta:
451-03-68/2022-14/200051
Financer:
MESTD - Ministry of Education, Science and Technological Development of Republic of Serbia
Program financ.:
Agreement on Realization and Financing of Scientific Research work of NIO
Številka projekta:
451-03-68/2022-14/200015
Financer:
ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
Številka projekta:
P1-0005
Naslov:
Funkcionalna živila in prehranska dopolnila
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