Monitoring of caffeine consumption effect on skin blood properties by diffuse reflectance spectroscopy

Milanič, Matija (avtor), Hren, Rok (avtor), Stergar, Jošt (avtor), Simončič, Urban (avtor)

Caffeine is the most widely consumed psychoactive substance worldwide, affecting numerous tissues and organs, with notable impacts on the central nervous system, heart, and blood vessels. The effect of caffeine on vascular smooth muscle cells is an initial transient contraction followed by significant vasodilatation. In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results demonstrate that cutaneous vasodynamics induced by caffeine consumption can be monitored by DRS, while changes in the control subject not consuming caffeine were insignificant.

• Jezik: Angleški jezik
• Ključne besede: medical physics, diffuse reflectance spectroscopy, caffeine, human skin
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FMF - Fakulteta za matematiko in fiziko
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: Str. 47-56
• Številčenje: Vol. 73, iss. 1
• PID: 20.500.12556/RUL-154948
• UDK: 543.424.4:616-073
• ISSN pri članku: 1802-9973
• DOI: 10.33549/physiolres.935138
• COBISS.SI-ID: 188395267
• Datum objave v RUL: 11.03.2024

Gradivo je del revije

• Naslov: Physiological Research
• Skrajšan naslov: Physiol. Res.
• Založnik: Institute of Physiology, Academy of Sciences of the Czech Republic
• ISSN: 1802-9973
• COBISS.SI-ID: 528962841

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: medicinska fizika, difuzna refleksijska spektroskopija, kofein, človeška koža

Projekti

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P1-0389
• Naslov: Medicinska fizika

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P1-0192
• Naslov: Svetloba in snov