Ovrednotenje uporabe konoplje za samozdravljenje med onkološkimi bolniki na Kliniki Golnik

Hladnik, Katarina (avtor), Tavčar, Eva (mentor), Horvat, Nejc (komentor)

Konoplja je rastlina, ki je v uporabi že tisočletja. Velikokrat jo dojemamo kot prepovedano drogo, saj je po slovenski zakonodaji še danes razvrščena v to skupino, vendar se vedno bolj prepoznava tudi njen terapevtski učinek. Uporablja se za lajšanje raznih kožnih stanj, za zdravljenje epilepsije, pri lajšanju kroničnih bolečin, slabosti in bruhanja, pri nevrodegenerativnih boleznih, raziskuje pa se celo njen učinek na zdravljenje raka. V presečni raziskavi smo s pomočjo vprašalnika, ki so ga izpolnjevali onkološki bolniki, ki se zdravijo na Kliniki Golnik, ovrednotili razširjenost uporabe konoplje za samozdravljenje. Vprašalnik smo vsebinsko razdelili na dva sklopa. V prvem sklopu smo se osredotočili na uporabo konoplje za samozdravljenje, v drugem sklopu pa smo zajeli sociodemografske podatke. Pred pričetkom raziskave smo vprašalnik pilotno testirali na naključnem vzorcu 10 ljudi, kar nam je pomagalo pri nadgradnji vprašalnika. Po 7 tednih anketiranja smo pridobili 127 veljavno izpolnjenih vprašalnikov. Rezultate smo obdelali z opisno ter sklepno statistiko v programu SPSS. Z analizo sociodemografskih podatkov smo ugotovili, da skoraj četrtina anketiranih onkoloških bolnikov uporablja konopljo za samozdravljenje, nekoliko pogosteje ženske uporabnice kot moški, s povprečno starostjo 60 let. Večina uporabnikov ima zaključeno srednjo oziroma poklicno šolo, največ ima diagnozo raka manj kot 6 mesecev ter v sistemskem zdravljenju raka prejemajo kemoterapijo. Kot najpogostejše neželene učinke zdravljenja raka, ki so jih občutili, so navedli slabost oziroma bruhanje in pomanjkanje apetita. S hi kvadrat testom smo ugotovili statistično značilno odvisnost med časom pričetka uporabe konoplje in kasnejšo uporabo konoplje med terapijo za zdravljenje raka. Hkrati pa tudi statistično značilno odvisnost med zaznanimi pozitivnimi učinki uporabe konoplje in pogostostjo uporabe konoplje. Z logistično regresijo smo ugotavljali, ali se onkološki bolniki, ki uživajo konopljo, razlikujejo od tistih, ki ne uživajo konoplje za samozdravljenje glede na sociodemografske podatke, kjer smo ugotovili, da čas, ki je pretekel od diagnoze napoveduje uporabo konoplje, kar pomeni, da onkološki bolniki, ki so imeli pred kratkim diagnosticiranega raka, konopljo za samozdravljenje uporabljajo pogosteje. Rezultate raziskave moramo zaradi subjektivnega dojemanja in nepodučenosti bolnikov interpretirati kritično. Nujne so nadaljnje raziskave na tem področju.

• Jezik: Slovenski jezik
• Ključne besede: konoplja, kanabinoidi, samozdravljenje, rak, vprašalnik
• Vrsta gradiva: Magistrsko delo/naloga
• Organizacija: FFA - Fakulteta za farmacijo
• Leto izida: 2023
• PID: 20.500.12556/RUL-152454
• Datum objave v RUL: 26.11.2023

Sekundarni jezik

• Jezik: Angleški jezik
• Naslov: Assessing the utilization of cannabis for self-medication among oncology patients at the University Clinic Golnik

Izvleček

Cannabis is a plant that has been in use for thousands of years. It is often perceived as an illegal drug, as it still classified, as such according to the Slovenian legislation, but its therapeutic effect is also increasingly recognized. It is used for the relief of various skin conditions, for treatment of epilepsy, relief of chronic pain, nausea and vomiting, neurodegenerative diseases, and even its effect on cancer treatment is being investigated. In a cross-sectional study, we evaluated the prevalence of cannabis use for self-medication using a questionnaire filled out by oncology patients being treated at the University Clinic Golnik. The content of the questionnaire was divided into two parts. In the first part, we focused on the use of cannabis for self-medication, while in the second part, we collected sociodemographic data. Before the start of the research, we pilot tested the questionnaire on a random sample of 10 people, which helped us optimise the questionnaire. After 7 weeks of surveying, we obtained 127 validly completed questionnaires. The results were processed with descriptive and inferential statistics in the SPSS program. By analysing sociodemographic data, we found that almost a quarter of the surveyed oncology patients use cannabis for self-medication, slightly more often women than men users, with an average age of 60. The majority of users have completed high school or vocational school, and have been diagnosed with cancer for less than 6 months and receive chemotherapy treatment. Most common side effects of cancer treatment that they experienced were nausea or vomiting and lack of appetite. With the chi-square test, we found statistically significant dependence between the start of cannabis use and the subsequent use of cannabis during cancer therapy. At the same time, we also found a statistically significant dependence between the perceived positive effects of cannabis use and frequency of cannabis use. Using logistic regression, we determined whether oncology patients, who use cannabis, differ from those who do not use cannabis for self-medication according to sociodemographic data. We found that the time that has passed since diagnosis predicts the use of cannabis, which means that oncology patients who have recently been diagnosed with cancer use cannabis more often for self-medication. The results of the research must be interpreted critically due to the subjective perception and lack of knowledge of the patients. Further research in this area is necessary.

• Ključne besede: cannabis, cannabinoids, self-medication, cancer, questionnaire