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Selected hematological, biochemical, and echocardiographic variables as predictors of survival in canine patients with myxomatous mitral valve disease and congestive heart failure
ID
Brložnik, Maja
(
Avtor
),
ID
Pečjak, Anja
(
Avtor
),
ID
Nemec Svete, Alenka
(
Avtor
),
ID
Domanjko-Petrič, Aleksandra
(
Avtor
)
PDF - Predstavitvena datoteka,
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(349,56 KB)
MD5: 6228AD5FE66535B63CCE9FC08AAF6192
URL - Izvorni URL, za dostop obiščite
https://www.sciencedirect.com/science/article/pii/S1760273423000103
Galerija slik
Izvleček
Introduction/objectives: We investigated the association of breed, age, weight, duration of therapy, and selected blood and echocardiographic variables with the survival of dogs with congestive heart failure (CHF) due to myxomatous mitral valve disease (MMVD). We also sought to identify differences in selected echocardiographic and routine blood variables between dogs with stable and unstable CHF and between hospitalized and nonhospitalized patients. Animals, materials and methods: This retrospective study included dogs with a complete cardiovascular workup. Blood analysis and the initial and final echocardiographic results were included. Covariates were analyzed using Cox proportional hazards models. Results: One hundred sixty-five dogs with MMVD were evaluated in this study: 96 stable patients and 69 unstable CHF patients. In total, 107 dogs (64.8%) died, and 58 (35.2%) were censored. The median survival time of the dogs that died was 11.5 months (range 11 days to 4.3 years). Unstable CHF patients had significantly higher neutrophils and lower potassium concentrations than stable CHF patients, and hospitalized patients had higher white blood cell, neutrophil, and monocyte counts, and urea and creatinine concentrations than nonhospitalized patients. Variables negatively associated with survival were older age, unstable CHF, duration of therapy, white blood cell count, urea concentration and left atrium to aorta ratio. Chihuahuas had a lower risk of death. Conclusions: Selected blood and echocardiographic variables distinguish dogs with stable and unstable CHF and predict survival.
Jezik:
Angleški jezik
Ključne besede:
chronic valvular disease
,
blood variables
,
cox proportional hazards 
models
,
dogs
,
blood
,
proportional hazards models
Vrsta gradiva:
Članek v reviji
Tipologija:
1.01 - Izvirni znanstveni članek
Organizacija:
VF - Veterinarska fakulteta
Status publikacije:
Objavljeno
Različica publikacije:
Objavljena publikacija
Leto izida:
2023
Št. strani:
Str. 18-29
Številčenje:
Vol. 46
PID:
20.500.12556/RUL-145113
UDK:
636.09:616
ISSN pri članku:
1875-0834
DOI:
10.1016/j.jvc.2023.03.001
COBISS.SI-ID:
144908035
Datum objave v RUL:
06.04.2023
Število ogledov:
625
Število prenosov:
109
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Objavi na:
Gradivo je del revije
Naslov:
Journal of veterinary cardiology
Založnik:
Elsevier
ISSN:
1875-0834
COBISS.SI-ID:
144899075
Licence
Licenca:
CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
Povezava:
http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
Opis:
Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.
Projekti
Financer:
ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
Številka projekta:
P4-0053
Naslov:
Endokrini, imunski in encimski odzivi pri zdravih in bolnih živalih
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