Reparative perineural hyperplasia in the gastric wall : a histologic mimic of perineural invasion

Bošnjak, Matic (avtor), Kojc, Nika (avtor)

Reparative perineural hyperplasia is an incidental and probably underreported reactive histologic finding thus far only reported in the setting of healing wounds or adjacent to a dermatofibroma in cutaneous specimens. It is characterized by a focal concentric proliferation of cytologically bland spindled perineurial cells and is hence considered a benign histologic mimic of neoplastic perineural invasion. Thus, it may present a diagnostic pitfall and we therefore consider it as a valuable entity to be aware of. To the best of our knowledge, this brief case report is the first to convey that reparative perineural hyperplasia may also occur in the gastrointestinal tract. It may therefore be a ubiquitous reactive histological phenomenon relating to previous surgical or traumatic wounds in various sites, that is, outside the thus far established setting of skin reexcision specimens.

• Jezik: Angleški jezik
• Ključne besede: perineural invasion, reparative perineural hyperplasia, immunohistochemistry, histologic mimic, gastrointestinal tract
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.03 - Kratki znanstveni prispevek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: Str. 903-905
• Številčenje: Vol. 29, iss. 8
• PID: 20.500.12556/RUL-144111
• UDK: 616.3
• ISSN pri članku: 1066-8969
• DOI: 10.1177/10668969211013469
• COBISS.SI-ID: 70124803
• Datum objave v RUL: 01.02.2023

Gradivo je del revije

• Naslov: International journal of surgical pathology
• Skrajšan naslov: Int. j. surg. pathol.
• Založnik: SAGE
• ISSN: 1066-8969
• COBISS.SI-ID: 75899

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: perinevralna invazija, reparativna perinevralna hiperplazija, imunohistokemija