The role of immune-related miRNAs in the pathology of kidney transplantation

Boštjančič, Emanuela (avtor), Večerić-Haler, Željka (avtor), Kojc, Nika (avtor)

MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in body fluids and stability. There is accumulating evidence that different miRNAs provide disease-specific signatures in liquid samples of distinct kidney injuries. Using experimental models and human samples, there have been numerous suggestions that immune-related miRNAs are also important contributors to the development of different kidney diseases as well as important markers for monitoring response after kidney transplantation. However, there are limited data for understanding their function in the molecular pathways of allograft pathologies. In our review, we focused on microRNAs that are related to different aspects of immune response after kidney transplantation.

• Jezik: Angleški jezik
• Ključne besede: microRNA (miRNA), kidney transplantation, immune response
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 15 str.
• Številčenje: Vol. 11, iss. 8, art. 1198
• PID: 20.500.12556/RUL-136014
• UDK: 616.6
• ISSN pri članku: 2218-273X
• DOI: 10.3390/biom11081198
• COBISS.SI-ID: 76937219
• Datum objave v RUL: 06.04.2022

Gradivo je del revije

• Naslov: Biomolecules
• Skrajšan naslov: Biomolecules
• Založnik: MDPI
• ISSN: 2218-273X
• COBISS.SI-ID: 519952921

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 12.08.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: mikroRNA (miRNA), presaditev ledvic, imunski odziv