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Novel unsteady state method of measuring permeability tested on fabric materials
ID Sitar, Anže (Avtor)

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Izvleček
The necessity of measuring permeability is encountered in number of applications and some of them have adequate measurement techniques available. However, in the fields of freeze drying, composite scaffolds, 3D printed materials, etc., the sample materials have unique shapes and sizes, which disables the use of standardized equipment. Hence, a novel method was developed to determine the permeability of a sample material by analyzing a high frequency unsteady state pressure measurement acquired during the permeation of a working fluid. The method is also suitable for in-line measurements due to the rapid acquisition and analysis. The developed method is novel, hence a comparison of the acquired results and the permeabilities measured with a standard device designed for measuring air permeability of fabric materials was made. Air was the permeating fluid in the novel unsteady state as well as in the referential steady state measurements. The measured permeabilities ranged from approximately 8 Da to 50 Da for the analyzed five fabric materials. The comparative analysis yielded an encouraging linear fit with a R2 = 0.98 by including only one unsteady state measurement of each fabric sample. In addition, the presented method was capable of detecting the difference in permeability of the freeze-dried 5 wt% and 12 wt% aqueous mannitol solutions, which exhibit different permeabilities due to the different porosities after the same process of lyophilization. The possibility of determining permeabilities of freeze-dried pharmaceuticals is essential for lyophilization process optimization.

Jezik:Angleški jezik
Ključne besede:novel measurement method, flow resistivity, permeability, unsteady state measurements, freeze-dried pharmaceuticals
Vrsta gradiva:Članek v reviji
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:FS - Fakulteta za strojništvo
Status publikacije:Objavljeno
Različica publikacije:Objavljena publikacija
Leto izida:2022
Št. strani:Str. 82-89
Številčenje:Vol. 68, no. 2
PID:20.500.12556/RUL-135441 Povezava se odpre v novem oknu
UDK:66.02:544.725.2
ISSN pri članku:0039-2480
DOI:10.5545/sv-jme.2021.7453 Povezava se odpre v novem oknu
COBISS.SI-ID:100930307 Povezava se odpre v novem oknu
Datum objave v RUL:15.03.2022
Število ogledov:654
Število prenosov:102
Metapodatki:XML DC-XML DC-RDF
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Gradivo je del revije

Naslov:Strojniški vestnik
Skrajšan naslov:Stroj. vestn.
Založnik:Zveza strojnih inženirjev in tehnikov Slovenije [etc.], = Association of Mechanical Engineers and Technicians of Slovenia [etc.
ISSN:0039-2480
COBISS.SI-ID:762116 Povezava se odpre v novem oknu

Licence

Licenca:CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:11.01.2022
Vezano na:Accepted for publication: 2022

Sekundarni jezik

Jezik:Slovenski jezik
Naslov:Nova nestacionarna metoda merjenja prepustnosti preverjena na tkaninah
Ključne besede:nova merilna metoda, permeabilnost, nestacionarna metoda merjenja, tkanine, liofilizirani proizvodi, prepustnost

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