Micronized, microencapsulated ferric iron supplementation in the form of >Your< Iron Syrup improves hemoglobin and ferritin levels in iron-deficient children : double-blind, randomized clinical study of efficacy and safety
ID Zečkanović, Aida (Author), ID Kavčič, Marko (Author), ID Prelog, Tomaž (Author), ID Šmid, Alenka (Author), ID Jazbec, Janez (Author)

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A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement >Your< Iron Syrup in the replenishment of iron stores and improvement of hematological parameters in iron-deficient children aged nine months to six years. We randomized 94 healthy children with iron deficiency in a ratio of 3:1 to either receive >Your< Iron Syrup or placebo. A 12-week supplementation with >Your< Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. >Your< Iron Syrup represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.

Keywords:iron deficiency, pediatric, children, supplementation, microencapsulated iron, syrup, liquid, food supplement
Work type:Article
Typology:1.01 - Original Scientific Article
Organization:FFA - Faculty of Pharmacy
Publication status:Published
Publication version:Version of Record
Number of pages:11 str.
Numbering:Vol. 13, iss. 4, art. 1087
PID:20.500.12556/RUL-135225 This link opens in a new window
ISSN on article:2072-6643
DOI:10.3390/nu13041087 This link opens in a new window
COBISS.SI-ID:64779523 This link opens in a new window
Publication date in RUL:01.03.2022
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Shortened title:Nutrients
COBISS.SI-ID:2948140 This link opens in a new window


License:CC BY 4.0, Creative Commons Attribution 4.0 International
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:01.04.2021

Secondary language

Keywords:pomanjkanje železa, pediatrija, otroci, mikrokapsule železa, sirup, tekočina, prehranski dodatki


Funder:Other - Other funder or multiple funders
Funding programme:PharmaLinea Ltd.

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