Micronized, microencapsulated ferric iron supplementation in the form of >Your< Iron Syrup improves hemoglobin and ferritin levels in iron-deficient children : double-blind, randomized clinical study of efficacy and safety

Zečkanović, Aida (avtor), Kavčič, Marko (avtor), Prelog, Tomaž (avtor), Šmid, Alenka (avtor), Jazbec, Janez (avtor)

A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement >Your< Iron Syrup in the replenishment of iron stores and improvement of hematological parameters in iron-deficient children aged nine months to six years. We randomized 94 healthy children with iron deficiency in a ratio of 3:1 to either receive >Your< Iron Syrup or placebo. A 12-week supplementation with >Your< Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. >Your< Iron Syrup represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.

• Jezik: Angleški jezik
• Ključne besede: iron deficiency, pediatric, children, supplementation, microencapsulated iron, syrup, liquid, food supplement
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FFA - Fakulteta za farmacijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 11 str.
• Številčenje: Vol. 13, iss. 4, art. 1087
• PID: 20.500.12556/RUL-135225
• UDK: 616-053.2
• ISSN pri članku: 2072-6643
• DOI: 10.3390/nu13041087
• COBISS.SI-ID: 64779523
• Datum objave v RUL: 01.03.2022

Gradivo je del revije

• Naslov: Nutrients
• Skrajšan naslov: Nutrients
• Založnik: MDPI
• ISSN: 2072-6643
• COBISS.SI-ID: 2948140

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.04.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: pomanjkanje železa, pediatrija, otroci, mikrokapsule železa, sirup, tekočina, prehranski dodatki

Projekti

• Financer: Drugi - Drug financer ali več financerjev
• Program financ.: PharmaLinea Ltd.