Micronized, microencapsulated ferric iron supplementation in the form of >Your< Iron Syrup improves hemoglobin and ferritin levels in iron-deficient children : double-blind, randomized clinical study of efficacy and safety

Zečkanović, Aida (author), Kavčič, Marko (author), Prelog, Tomaž (author), Šmid, Alenka (author), Jazbec, Janez (author)

A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement >Your< Iron Syrup in the replenishment of iron stores and improvement of hematological parameters in iron-deficient children aged nine months to six years. We randomized 94 healthy children with iron deficiency in a ratio of 3:1 to either receive >Your< Iron Syrup or placebo. A 12-week supplementation with >Your< Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. >Your< Iron Syrup represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.

• Language: English
• Keywords: iron deficiency, pediatric, children, supplementation, microencapsulated iron, syrup, liquid, food supplement
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FFA - Faculty of Pharmacy
• Publication status: Published
• Publication version: Version of Record
• Year: 2021
• Number of pages: 11 str.
• Numbering: Vol. 13, iss. 4, art. 1087
• PID: 20.500.12556/RUL-135225
• UDC: 616-053.2
• ISSN on article: 2072-6643
• DOI: 10.3390/nu13041087
• COBISS.SI-ID: 64779523
• Publication date in RUL: 01.03.2022

Record is a part of a journal

• Title: Nutrients
• Shortened title: Nutrients
• Publisher: MDPI
• ISSN: 2072-6643
• COBISS.SI-ID: 2948140

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 01.04.2021

Secondary language

• Language: Slovenian
• Keywords: pomanjkanje železa, pediatrija, otroci, mikrokapsule železa, sirup, tekočina, prehranski dodatki

Projects

• Funder: Other - Other funder or multiple funders
• Funding programme: PharmaLinea Ltd.