Introduction: Toxoplasmosis is a disease, caused by a parasite Toxoplasma gondii. Humans usually get infected by eating raw or undercooked meat, by ingesting contaminated water, fruits, vegetables, through contact with contaminated soil or infected cat faeces. The infection can also be transmitted through transplanted organs, blood transfusions or through infected mother to the fetus. If a woman gets infected for the first time during pregnancy, this is called a primary infection. To determine a pregnant woman's infection, toxoplasmosis screening is performed. If the infection is confirmed, the pregnant woman should be treated immediately with appropriate therapy. If the infection gets vertically transmitted to the fetus, the newborn also has to be treated after birth. Most common drugs in use for treating toxoplasmosis are Spiramycin, Pyrimethamine and Sulfadiazine. Prevention is the most important. We need to educate women on how to protect themselves from infection while also screen them for toxoplasmosis. Purpose: The purpose of this diploma thesis is to determine based on existing research and available data, the incidence of toxoplasmosis among pregnant women and newborns in Slovenia and whether its incidence has increased or decreased over the years. Methods: We used a descriptive method of work. We presented information about toxoplasmosis and its’ impact on pregnant women and newborns. We also drew information from the NIJZ data portal. We searched for English and Slovenian literature, with help from PubMed, Google Scholar, ScienceDirect and Wiley Online Library databases. Restrictive criteria in the search were full accessibility of articles, linguistic relevance and relevance of the content of articles. Results: The incidence of primary toxoplasmosis in pregnancy was last investigated in 2004. Data shows that the incidence of PTN in Slovenia increased sharply, but then began to decline and at the last measurement amounted to 0.31%. Congenital toxoplasmosis is about 1 in 10 000 live births in Slovenia, which is similar to Austria. Discussion and conclusion: Based on older research and the situation in Austria, we can conclude that the incidence of PTN has continued to decline over the years. The incidence of congenital toxoplasmosis in Slovenia has also decreased significantly over the years, which can be largely attributed to the mandatory screening of pregnant women for toxoplasmosis. Toxoplasmosis infection is still a global public health problem. The most important approach to dealing with this infection is primarily prevention, screening and, in the case of a pregnant woman's infection, immediate treatment.
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