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Obesity with high body mass index does not influence sperm retrieval in males with azoospermia
Pavan-Jukić, Doroteja (Avtor), Starc, Andrej (Avtor), Štubljar, David (Avtor), Jukić, Tomislav (Avtor)

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URLURL - Izvorni URL, za dostop obiščite https://www.medscimonit.com/abstract/index/idArt/923060 Povezava se odpre v novem oknu

Izvleček
Background: The aim of this study was to evaluate the influence of male body mass index (BMI) on the retrieval of sperm from azoospermic patients who were undergoing testicular sperm extraction (TESE). Material/Methods: The study included retrospective data of male patients suffering from non-obstructive azoospermia (NOA). Age, BMI, testicular volumes, the serum concentration of the follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and prolactin were investigated and collected. Results: A total of 75 azoospermic males were evaluated between 2014 and 2019, including 35 patients (46.7%) with positive sperm retrieval. The majority of patients (57.3%) had normal BMI (between 20 kg/m2 and 25 kg/m2) or first degree obesity (from 25 kg/m2 to 30 kg/m2). No statistically significant correlation between BMI and positive sperm retrieval or hormone levels (LH, FSH, SHBG, prolactin) were found. However, lower serum testosterone levels were observed in patients with higher BMI (P=0.035). Receiver operating characteristic curve analysis showed that none of the hormones could potentially predict the positive outcome of TESE. Conclusions: The hormonal levels or patient's BMI could not predict positive sperm retrieval outcome, however a negative correlation between serum testosterone and BMI levels was calculated implicating influence on fertility.

Jezik:Angleški jezik
Ključne besede:azoospermia, body mass index, obesity, sperm retrieval, testosterone
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:ZF - Zdravstvena fakulteta
Leto izida:2020
Št. strani:str. 1-6, e923060
Številčenje:Vol. 26
UDK:616.697:613.25
ISSN pri članku:1643-3750
DOI:10.12659/MSM.923060 Povezava se odpre v novem oknu
COBISS.SI-ID:12813315 Povezava se odpre v novem oknu
Licenca:CC BY-NC-ND 4.0
To delo je dosegljivo pod licenco Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
Število ogledov:86
Število prenosov:53
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Naslov:Medical Science Monitor
Skrajšan naslov:Med. Sci. Monit.
Založnik:Medical Science Int.
ISSN:1643-3750
COBISS.SI-ID:31216089 Povezava se odpre v novem oknu

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