The thesis describes the use of big data in healthcare. The purpose of this research is to determine the relevance of the existing legal regime and to present possible amendments regarding legislation in the field of privacy protection. It is necessary to ensure the right to privacy, while preserving the benefits of new technology innovations. We need excellent legal regulation for future challenges. This study emphasizes focus on the collective aspects of the right to privacy, relevance of provisions regarding suitable security and mutual exchange of information, preparation of a comprehensive legal framework regarding electronic health records and e-health services, importance of a legal framework regarding the use of health data for research purposes, highlights changes in health insurance sector and underlines significance of quick distribution and overall interconnectivity of the data. A special discussion is intended regarding the regulation of personal data, since non-personal data can also create conclusions of a personal nature. Furthermore, due to the circular nature of the data, improved control over compliance with the legislation and financial reinforcement of the supervisory authorities are recommended. The thesis therefore outlines legal issues that, along with ethical dilemmas, appear in the field of big data and privacy in healthcare. The current legal framework is appropriate, but in certain places needs some conceptual changes. The thesis coincides with the application of the new General Data Protection Regulation.