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PhD theses (2)
Kaja Bergant Loboda:
Načrtovanje in optimizacija katalitičnih zaviralcev človeške DNA topoizomeraze ▫$II\alpha$▫ kot potencialnih protirakavih učinkovin
Anja Kolarič:
Uporaba kemoinformatičnih in strukturno podprtih in silico metod za načrtovanje zaviralcev bakterijske DNA giraze ter modulatorjev kemokinskih receptorjev CXCR3 in CXCR4
Other documents (9)
Maja Kokot, Matjaž Weiss, Irena Zdovc, Lidija Šenerović, Natasa Radakovic, Marko Anderluh, Nikola Minovski, Martina Hrast:
Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy
Anja Kolarič, Thomas Germe, Martina Hrast, Clare E. M. Stevenson, David M. Lawson, Nicolas P. Burton, Judit Vörös, Anthony Maxwell, Nikola Minovski, Marko Anderluh:
Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds
Anja Kolarič, Maja Kokot, Martina Hrast, Matjaž Weiss, Irena Zdovc, Jurij Trontelj, Simon Žakelj, Marko Anderluh, Nikola Minovski:
A fine-tuned lipophilicity/hydrophilicity ratio governs antibacterial potency and selectivity of bifurcated halogen bond-forming NBTIs
Maja Kokot, Marko Anderluh, Martina Hrast, Nikola Minovski:
The structural features of novel bacterial topoisomerase inhibitors that define their activity on topoisomerase IV
Maja Kokot, Matjaž Weiss, Irena Zdovc, Martina Hrast, Marko Anderluh, Nikola Minovski:
Structurally optimized potent dual-targeting NBTI antibacterials with an enhanced bifurcated halogen-bonding propensity
Anja Kolarič, Marko Anderluh, Nikola Minovski:
Two-decades of successful SAR-grounded stories of the novel bacterial topoisomerase inhibitors (NBTIs)
Maja Kokot, Doroteja Novak, Irena Zdovc, Marko Anderluh, Martina Hrast, Nikola Minovski:
Exploring alternative pathways to target bacterial type II topoisomerases using NBTI antibacterials: beyond halogen-bonding interactions
Maja Kokot, Nikola Minovski:
Dynamic profiling and binding affinity prediction of NBTI antibacterials against DNA gyrase enzyme by multidimensional machine learning and molecular dynamics simulations
Maša Zorman, Maja Kokot, Irena Zdovc, Lidija Šenerović, Mina Mandic, Nace Zidar, Andrej Emanuel Cotman, Martina Durcik, Lucija Peterlin-Mašič, Nikola Minovski, Marko Anderluh, Martina Hrast:
Enhancing antibacterial efficacy