Introduction: The carpal tunnel syndrome is the most common peripheral compression neuropathy of the upper limb and shows itself as a sensory and motor disorder, which occurs due to compression and traction of the median nerve in the carpal tunnel and covers 90 % of all compression neuropathies. Sensory impairment reflects itself as an occurrence of paraesthesia (tingling), itchiness, pain, and numbness down the median nerve, which innervate the thumb, index finger, middle finger, and the radial side of the ring finger. These symptoms often occur during the night but pass as soon as the affected hand is shaken. The motor impairment is reflected in the reduced power of the grasp with the reduced function of the affected hand. This leads to weak muscles that perform the opposition of the thumb and it also leads to the atrophy of the thenar, which results in suddenly dropping things from hands. Purpose: Based on the overview of literature, this paper wishes to present the effectiveness of individual physiotherapeutic procedures in treating the syndrome of the carpal tunnel. Methods: Literature was found with the help of electronic databases Cochrane library, PEDro in PubMed while we focused on articles published from 2010 to 2017. Results: We chose 12 randomized controlled trials that were published in English. The authors of these experiments studied improvements by including various manual techniques and the tendons and nerve gliding exercises. They discovered greater improvements in favour of the procedures of the mobilization of the median nerve, wrist bone mobilization, massage, manipulation of the fascia, ischemic compression therapies, and the tendons and the nerve gliding exercises. Discussion and conclusion: It is hard to compare these results, since the treatment procedures differed from one another. Based on these results we cannot give the most effective approach, but we can conclude that these approaches are more beneficial than conventional physiotherapy, which also have been effective in improving the symptoms and the functions of the patients. In order to prove efficiency of above-mentioned physiotherapeutic procedures further research is necessary.