People have adjusted to technological changes and accepted a sedentary way of life. Nowadays, we spend most of our time at work and neglect our health by sitting throughout most of the day. Many times, we do it in an incorrect position which is not optimal for our health. This causes many negative effects on our mental and physical health, which can be minimalised with a regular physical activity. The thesis is a monographic type. We reviewed literature and research focusing on the chosen subject. The purpose of the thesis is to present issues of a modern workplace and its negative effects. Moreover, we defined the optimal sitting position during work and ways to relieve tension in the body. Lastly, one of our main goals was to describe the promotion of worksite health and exercise and to define positive effects of workplace exercise. It was discovered that positive effects of exercise include improvement in both mental and physical health. Exercise decreases pain in musculoskeletal structures, mostly in lumbar spine, shoulders and neck. Many volunteers who did workplace exercise, increased the physical activity in their free time as well, thus there are findings of many pupils improving their body composition. Studies also show lower fat and cholesterol percentage and many people report losing weight and inches around waist. In addition, the weight drop reduces the risk of developing type 2 diabetes. Besides physical health benefits, studies show lower work absenteeism and improvements in productivity and overall well-being.