Introduction: Pregnancy means changed (non-ill) condition of the pregnant woman, accompanied by different changes which because of various myths, taboos and cultural and historical beliefs still have a negative influence on sexual intimacy in a relationship. Especially health care workers and nurses have key role to help disappear myths, taboos, and beliefs with proactive approach with the help of PLISSIT model. Purpose: The purpose of the thesis is to study the impact of pregnancy on sex life and introduce the corresponding changes that occur during each trimester and present the influence and assignments of nurses in the field of sexuality during pregnancy. Methods: Descriptive working method is used in the thesis with which it is transparently and systematically described the domestic and foreign scientific and professional literature. Because it is a theoretical thesis it has been done a critical review of selected literature with key words and phrases that were (sex during pregnancy, the role of nurses in the field of sexuality during pregnancy and PLISSIT model) searched in databases COBIB.SI, CINAHL and Medline in the period between 2014 and 2016. Results: During pregnancy sexual activity and sexual needs may change; especially in women with pregnancy progressing from the first trimester on the sex drive declines, and in men mostly only in the third trimester. The decrease in desire and sexual activity is affected by fears and taboos and cultural prejudices, making advisory and health educational an important role of the nurse. The nurse can use a variety of tools, such as model PLISSIT to assists couples in the acquisition of knowledge about sexuality in pregnancy and to explore opportunities in sexual practices. The nurse contributes significantly to maintaining the quality of sexual life of couples. Discussion and conclusion: Changed partnership because of pregnancy often causes fears in partners. One of them is sex during pregnancy, which requires changed sex life of partners with appropriate positions. Many of the changes felt by pregnant woman, in fact characterize her unique period (pregnancy), in which it should be as much time for bed activities as possible, and much less for a different burdes because of various myths, taboos and cultural and historical beliefs. The key for solving sexual problems in pregnancy period is communication between partners and the inclusion of a therapist. The partners, who expect offspring, must follow the instructions of the selected family doctor, gynecologist (about sex during pregnancy) and nurse. With consultational, educational and health-educational role with pregnant women nurse try to dispel myths, taboos and beliefs through the use of PLISSIT model and with a proactive approach to prepare them for a relaxed childbirth.