Introduction: Ankle sprain is one of the most common injuries in the active population. Effective physiotherapy procedures are very important to prevent chronic ankle disorders, such as pain, swelling, restricted range of motion or feelings of giving way and perceived ankle instability. Purpose: The dissertation is focused on literature review of randomised controlled trials, which compared effects of different physiotherapy procedures that are recommended after subacute ankle sprain. Methods: Literature was selected in Internet databases PEDro, Pub Med, ScienceDirect and Cinahl and were limited to a search of Slovenian and English languages. For the literature review we consider only randomised controlled trials with six or more scores in the PEDro scale. Results: In the literature review were included eight randomised controlled trials, that were published between years 2007 and 2015. Researches included the following physiotherapy procedures: manual therapy, resistance training, techniques of proprioceptive neuromuscular facilitation, balance and proprioceptive training and plyometric training. Studies differentiate for the length of duration (for four days to seven months); for the times of the executed physiotherapy procedures (once to seven times per week); and for the duration of the physiotherapy procedures (20 to 30 minutes). Based on the results of these randomised controlled trials is evident that all physiotherapy procedures were effective in treating subacute ankle sprain. These are the benefits on the ankle: reduced pain, improved perception of stability, restored range of motion, increased strength, a better balance, proprioception and a more functional performance of daily living. Discussion and conclusion: Based on the studies we can suppose that the most effective procedure does not consist in one physiotherapy procedure, but it is more effective to treat ankle sprain when applying training programs with manual therapy. At the same time, we have to take into account, that dissertation's results can be the consequence of spontaneous recovery during ongoing researches, since in some control groups partial improvements were noticed.